[ANSWER]High Dose Methotrexate PowerPoint: High Dose Methotrexate: A Resource for Registered Nurses Working in an Oncology/Hematology Ward 

[ANSWER PREVIEW]Patients receiving HD MTX also usually receive leucovorin Registered Nurses Working (calcium folinate)

Patients receiving HD MTX also usually receive leucovorin Registered Nurses Working (calcium folinate). Leucovorin is administered to mitigate the risk of the toxicity associated with HD MTX (Howard et al., 2016). The administration of the drug often involves an IV bolus (eviQ, 2020). Ordinarily, the administration begins exactly 24 hours following the start of the IV infusion of HD MTX. In other words, it is administered on Day 2. This means that the time at which HD MTX administration begins should be documented to ensure leucovorin administration starts at the right time.

Leucovorin should be administered over 1-2 minutes. In addition, the IV line should be flushed with sodium chloride Registered Nurses Working (~50 mL) 0.9%. For the first 4 doses, leucovorin is administered at a rate of 50 mg for every 6 hours; afterwards, it is administered at a rate of 30 mg every 6 hours until the level of methotrexate goes below 0.05 µmol/L…[Buy Full Answer for Just USD 9: 1565 WORDS]

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