[ANSWER]NSC2500 Assignment 1 – Prostate Cancer and Mitotic Spindle Inhibitors: Pathophysiology and Pharmacology

[ANSWER PREVIEW ON Prostate Cancer and Mitotic Spindle Inhibitors]

In the prostate gland, the production of seminal fluid occurs specifically in the glandular tissue, which primarily makes up the gland (Simoes et al., 2018). This tissue can be affected by various pathological events, notably prostatitis (inflammation due to acute or chronic bacterial infection), benign hyperplasia (tissue enlargement due to cell proliferation), and malignant cancer (Coleman, 2018).

For purposes of this paper, attention is specifically paid to malignancy. In malignant cases, prostate cancer begins in the glandular tissue. The cancer is preceded by the mutation of glandular cells, typically starting with cells in the peripheral zone (Leslie et al., 2021). The multiplication of the cancer cells causes them to spread to the surrounding prostatic tissue, resulting in tumour formation.

Tumour formation subsequently leads to the enlargement of the prostate gland (Simoes et al., 2018). As the prostate gland is located below the urinary blander, this enlargement obstructs the urethra, ultimately resulting in urination difficulties and disrupted urine flow, which are among the major clinical manifestations of prostate cancer (Coleman, 2018). Other notable clinical indicators of prostate cancer include elevated levels of prostate specific antigen in the blood, invasive growth of the glandular tissue, increased mitotic cells…[Buy Full Answer for Just USD 9: 1965 WORDS]

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Type: Essay

Word Count: 1965

Grade/Mark: 92 (Distinction)

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