[ANSWER]Bioscience Assignment 2 Case Study – Gentamicin

[ANSWER PREVIEW] on Gentamicin

Gentamicin is among the topical antibiotics used to treat bacterial eye infections (Bullock & Manias, 2017). The medication is particularly active against gram-negative bacteria. An aminoglycoside antibiotic, the drug works by binding the aminoglycoside to the bacteria’s ribosome 30S subunit, effectively interfering with mRNA translation and inhibiting protein synthesis (Lin et al., 2011). How bacterial death occurs is yet to be known with certainty. One theory is that the inhibition of protein synthesis enhances the impermeability of the cell wall, while another theory links bacterial death to the build-up of reactive oxygen species that occurs as a result of protein depletion (Chaves & Tadi, 2021). Learn more about Gentamicin

Name two adverse reactions of this drug?

• Toxicity (especially ototoxicity and nephrotoxicity): Systemic absorption of the drug is rare when administered topically, but if it occurs, toxicity can occur (Hayward et al., 2018).
• Skin irritation or itching (Watson et al., 2018).[Buy Full Answer for Just USD 9: 1705 WORDS]

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Type: Essay

Word Count: 1705

Grade/Mark: 89 (Distinction)

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